Lexus offers two flavors for their mid-size executive range. First is the comfort-oriented ES350 and this: the GS350. One major difference between the two is the drivetrain layout. The GS350 comes with rear wheel drive and has more sporting intentions similar to European cars in its class. Those looking for an efficient executive car can check out the GS450h. It offers similar performance to the GS350 with the benefit of hybrid efficiency.